I hate to say it, but so far, there are no “best” anti-aging face creams. Most creams aren’t strong enough to stimulate collagen and tighten the skin. The only things able to do that are lasers, and the RF (radio frequency) devices like Thermage.
Retin A cream is the exception to this. It can stimulate collagen and make your skin younger, but it’s a pain to use. It makes your skin very red and flakey at first. It also thins the skin, which is an undesirable side effect. You need a prescription to get Retin A in the U.S. or you can order it overseas without a prescription from Four Corners UK Pharmacy in England.
Retinols are just milder versions of Retin A. They don’t do much, either.
Dr. Perricone’s skin care line is excellent. He is a genius with skin care, the first doctor to figure out how damaging sugar is to the skin. He come up with a diet that actually works to make you look up to a decade younger and has the patient before and after photos to prove this. His book “The Wrinkle Cure” remains the best anti-aging book for younger skin ever written.
I’ve used Perricone’s High Potency Amine Facelight. His products do make your skin look fresher—which makes you look younger—BUT creams alone will not reduce sagging skin or tighten jowls, etc. It’s just not going to happen. Think of it this way: if creams worked to tighten skin, no one would need facelifts.
There is a new face cream that sounds promising. It’s called Glyterra gL. It works on the principle of repairing the damage that sugars cause to your skin. I haven’t tried it yet, but I’m going to as soon as I’m finished with the Tria Age Defying Laser review I’m doing.
Another new “revolutionary” anti-aging cream that might work is MitoQ cream. I haven’t tried it.
What My Lips Wore 